Workshop

25th Workshop

25th Workshop
“Softness and functions of biological molecules
under various environments”

【 Date 】	September 20, 2017
【 Venue 】	Kurokami North Campus, Kumamoto University 2-39-1 Kurokami, Chuo-ku, Kumamoto, 860-8555 JAPAN
【 Access 】	http://ewww.kumamoto-u.ac.jp/en/about/access/access_map/
【 Organizers 】	Satoshi Takahashi (Tohoku Univ.), Ryota Iino (Okazaki Institute for Integrative Bioscience)
【 Registration 】	Needs registration to BSJ55. (On-site registration available.) http://www.aeplan.co.jp/bsj2017/en/index.html
【 Co-sponsor 】	Biophysical Society of Japan
【 Overview 】	Biological systems express their functions through the 　coordinated dynamics of soft biological macromolecules in various environments. In this symposium, we ask young investigators to present their recent investigations based on molecular dynamics simulations, in cell NMR, high speed AFM and advanced optical microscopies and to discuss the current understanding and future perspectives of their target biological systems.

8:45-9:10	NMR approaches to investigate protein folding and dynamics in the crowded intracellular environment ◯Yutaka Ito (Dept. Chemistry, Tokyo Metropolitan Univ.)
9:10-9:35	Deciphering the heterogeneous dynamics of proteins from the analysis of millisecond-long molecular dynamics simulations ◯Toshifumi Mori^1,2, Shinji Saito^1,2 (¹IMS, ²SOKENDAI)
9:35-10:00	Ultrahigh-speed single-particle tracking by interferometric scattering (iSCAT) microscopy ◯Chia-Lung Hsieh (Institute of Atomic and Molecular Sciences, Academia Sinica)
10:00-10:25	Raman scattering microscopy and alkyne-tag for imaging and screening of bio-active small molecules ◯Jun Ando^1,2,3,4, Katsumasa Fujita^1,2, Mikiko Sodeoka^2,3 (¹Dept. of Applied Physics, Osaka Univ., ²AMED-CREST, AMED,³RIKEN, ⁴Institute for Molecular Science)
10:25-10:50	High-Speed AFM Observation of Domain Flexibility Related to Enzymatic Function of CRISPR-Cas9 ◯Takayuki Uchihashi¹, Mikihiro Shibata^2,3, Hiroshi Nishimasu^4,5, Noriyuki Kodera^3,5, Seiichi Hirano⁴, Toshio Ando^3,6, Osamu Nureki⁴ (¹Dept. Phys., Nagoya Univ., ²ISFS, Kanazawa Univ., ³Bio-AFM FRC, Kanazawa Univ., ⁴Dept. Biol., Univ. Tokyo, ⁵JST-PRESTO, ⁶JST-CREST)
10:50-11:15	Chemo-mechanical coupling mechanisms of linear and rotary molecular motors revealed by high-speed singlemolecule imaging analysis ◯Ryota Iino^1,2,3 (¹OIIB, NINS, ²IMS, NINS, ³SOKENDAI)