Workshop

23rd Workshop

23rd Workshop
“Flexibility and function of proteins”

【 Date 】	June 20, 2017
【 Venue 】	Sendai International Center
【 Access 】	Aobayama, Aoba-ku, Sendai 980-0856 Japan http://www.aobayama.jp/english/access/
【 Organizer 】	Yasuhisa Mizutani (Osaka Univ.)
【 Registration 】	Needs registration to PSSJ2017. (On-site registration available.) http://www.aeplan.co.jp/pssj2017/en/registration.html
【 Co-sponsor 】	Protein Science Society of Japan
【 Overview 】	Proteins function by changing their three-dimensional structure. Sophisticated mechanisms are involved in proteins to excellently function in cells, of which environment is heterogeneous, condensed, and full of thermal noise. To clarify the mechanism, it is necessary to collaborate a variety of advanced approaches. In this workshop, we discuss flexibility of protein and the functioning mechanism produced by the flexibility, which have been clarified by cuttingedge works of theory, measurement and creation.

16:00-16:10	Opening Remarks
16:10-16:35	“Sensing mechanism of heme-based gas sensor proteins” ○Yasuhisa Mizutani (Grad Sch. of Sci., Osaka Univ.)
16:35-17:00	“Soft structure-function relationship revealed by functional conversion of photoreceptive proteins” ○Hideki Kandori (Nagoya Inst. Tech.)
17:00-17:15	“Protein flexibility and characters of transition metal ions in protein core: An experimental study using thiol-subtilisin as a model protein” ○Takashi Matsuo, Isamu Shobu, Masaya Ishida, Takamasa Kono, Shun Hirota (Grad. Sch. Mater. Sci., Nara Institute of Sience and Technology)
17:15-17:40	“Microsecond dynamics of proteins studied by two-dimensional fluorescence lifetime correlation spectroscopy” ○Tahei Tahara (RIKEN)
17:40-17:55	“Ultrafast intersegmental transfer of a tumor suppressor p53 characterized by ensemble and single-molecule fluorescence spectroscopy” ○Yuji Itoh^1,2, Agato Murata^1,2, Satoshi Takahashi¹, Kiyoto Kamagata¹ (¹IMRAM, Tohoku Univ., ²Grad. Sch. of Sci., Tohoku Univ.)
17:55-18:20	“Protein flexibility, dissociation and association investigated by PaCS-MD” ○Akio Kitao (Inst. of Mole. Cell. Biosci., The Univ. of Tokyo)
18:20	Closing Remarks