理論と実験の協奏による柔らかな分子系の機能の科学-文部科学省科学研究費補助金「新学術領域研究」領域代表者 田原太平 (平成25-29年度) やわぶん

   

23rd Workshop

23rd Workshop
“Flexibility and function of proteins”
【 Date 】 June 20, 2017
【 Venue 】 Sendai International Center
【 Access 】 Aobayama, Aoba-ku, Sendai 980-0856 Japan
http://www.aobayama.jp/english/access/
【 Organizer 】 Yasuhisa Mizutani (Osaka Univ.)
【 Registration 】 Needs registration to PSSJ2017. (On-site registration available.)
http://www.aeplan.co.jp/pssj2017/en/registration.html
【 Co-sponsor 】 Protein Science Society of Japan
【 Overview 】 Proteins function by changing their three-dimensional structure. Sophisticated mechanisms are involved in proteins to excellently function in cells, of which environment is heterogeneous, condensed, and full of thermal noise. To clarify the mechanism, it is necessary to collaborate a variety of advanced approaches. In this workshop, we discuss flexibility of protein and the functioning mechanism produced by the flexibility, which have been clarified by cuttingedge works of theory, measurement and creation.

Program: June 20

16:00-16:10 Opening Remarks
16:10-16:35 “Sensing mechanism of heme-based gas sensor proteins”
○Yasuhisa Mizutani (Grad Sch. of Sci., Osaka Univ.)
16:35-17:00 “Soft structure-function relationship revealed by functional conversion of photoreceptive proteins”
○Hideki Kandori (Nagoya Inst. Tech.)
17:00-17:15 “Protein flexibility and characters of transition metal ions in protein core: An experimental study using thiol-subtilisin as a model protein”
○Takashi Matsuo, Isamu Shobu, Masaya Ishida, Takamasa Kono, Shun Hirota (Grad. Sch. Mater. Sci., Nara Institute of Sience and Technology)
17:15-17:40 “Microsecond dynamics of proteins studied by two-dimensional fluorescence lifetime correlation spectroscopy”
○Tahei Tahara (RIKEN)
17:40-17:55 “Ultrafast intersegmental transfer of a tumor suppressor p53 characterized by ensemble and single-molecule fluorescence spectroscopy”
○Yuji Itoh1,2, Agato Murata1,2, Satoshi Takahashi1, Kiyoto Kamagata1 (1IMRAM, Tohoku Univ., 2Grad. Sch. of Sci., Tohoku Univ.)
17:55-18:20 “Protein flexibility, dissociation and association investigated by PaCS-MD”
○Akio Kitao (Inst. of Mole. Cell. Biosci., The Univ. of Tokyo)
18:20 Closing Remarks
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